| |
 New chemistry.
The
active ingredient in AVENGE is imidacloprid, belonging
to the class of chemical insecticides known as the neonicotinoids.
It is the first new molecule in sheep lice control for
more than five years. It acts selectively on the central
nervous system of lice for rapid control.
New solution.
AVENGE controls lice resistant to other chemical groups:
- It delivers a completely new mode-of-action for sheep
lice control, making it a vital tool for insecticide
resistance management.
- It provides uncompromising lice control while breaking
the resistance cycle.
- The introduction of imidacloprid as a first-in-class
active ingredient foreshadows a new era in sheep lice
control.
New standard.
| TABLE 1: Mode of action
and reported first usage of some common sheep lousicides |
| Chemical class |
Chemicals
|
Site of action
|
Reported for
use against sheep lice
in Australia |
| Neonicotinoids |
Imidacloprid |
Nervous system |
2009 |
| Spinosyns |
Spinosad |
Nervous system |
2003ƒ |
| Macrocyclic lactones (avermectins) |
Ivermectin |
Nervous system
and muscles |
1995* |
| Insect growth regulators |
Diflubenzuron Triflumuron |
Growth regulation |
1993^ |
| Synthetic pyrethroids |
Cypermethrin Deltamethrin |
Nervous system |
1978Δ |
| Organophosphates |
Diazinon Temephos |
Nervous system |
1957† |
| ƒ |
APVMA PUBCRIS website: http://services.apvma.gov.au/PubcrisWebClient/details.do?view=summary&pcode=56875.
Accessed on 13 July 2009. |
| * |
Resistance and the control of
sheep ectoparasites, Levott, G.L. International
Journal for Parasitology, vol. 25, p1355, 1995. |
| ^ |
Bayer Australia Limited. Data
on file. |
| Δ |
The efficiency of cypermethrin
(NRDC 149) for the treatment and eradication of the
sheep louse Damalinia ovis, Hall, C.A., Australian
Veterinary Journal, vol. 54,
October, p471, 1978. |
| † |
Recent advances in the control
of the ectoparasites of sheep, Brander, G.C., The
Australian Veterinary Journal, December, p318,
1957. |
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